3-Morpholinobenzanthrone

Names

[ Name ]:
3-Morpholinobenzanthrone

[Synonym ]:
3-Morpholino-7H-benz[de]anthracen-7-one
3-morpholin-4-ylbenzo[b]phenalen-7-one

Biological Activity

[Description]:

3-Morpholinobenzanthrone is a fluorescent membrane probe, possessing higher dipole moment values in the excited-state than in the ground-state[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. B.Siddlingeshwar, et al. Photophysical characteristics of three novel benzanthrone derivatives: Experimental and theoretical estimation of dipole moments. J Quant Spectrosc Radiat Transf. 2011 Feb., 112 (3), 448-456.

Chemical & Physical Properties

[ Density]:
1.301g/cm3

[ Boiling Point ]:
556.5ºC at 760 mmHg

[ Molecular Formula ]:
C₂₁H₁₇NO₂

[ Molecular Weight ]:
315.36500

[ Flash Point ]:
290.4ºC

[ Exact Mass ]:
315.12600

[ PSA ]:
29.54000

[ LogP ]:
3.95280

[ Index of Refraction ]:
1.699

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

HIV-1 fusion inhibitor peptides enfuvirtide and T-1249 interact with erythrocyte and lymphocyte membranes.

PLoS ONE 5 , e9830, (2010)

Enfuvirtide and T-1249 are two HIV-1 fusion inhibitor peptides that bind to gp41 and prevent its fusogenic conformation, inhibiting viral entry into host cells. Previous studies established the relati...

Evaluation of a fluorescent derivative of AMD3100 and its interaction with the CXCR4 chemokine receptor.

ChemBioChem. 12 , 2692-2698, (2011)

AMD3100 is a potent and selective antagonist of the CXCR4 receptor; it has been shown to block the route of entry of HIV into host T-cells. This compound and its analogues have since been found to act...

Suitability of various membrane lipophilic probes for the detection of trogocytosis by flow cytometry.

Cytometry 75 , 380-389, (2009)

Trogocytosis is a recently discovered phenomenon whereby lymphocytes capture fragments of the plasma membrane from antigen presenting cells (APCs). Using APCs labeled with widely used fluorescent lipo...

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.