Diapocynin

Names

[ Name ]:
Diapocynin

[Synonym ]:
diapocynin
dehydrodiacetovanillone
1,1'-[6,6'-dihydroxy-5,5'-dimethoxy-1,1'-biphenyl-3,3'-diyl]diethanone
5,5'-Diacetyl-3,3'-dimethoxy-biphenyl-2,2'-diol

Biological Activity

[Description]:

Diapocynin (Dehydrodiacetovanillone), a dimeric derivative of Apocynin, is an orally active NADPH oxidase inhibitor. Diapocynin has anti-inflammatory, neuroprotection and antioxidant activities[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Research Areas >> Neurological Disease

[References]

[1]. Marson Putra, et al. Diapocynin, an NADPH oxidase inhibitor, counteracts diisopropylfluorophosphate-induced long-term neurotoxicity in the rat model. Ann N Y Acad Sci. 2020 Nov;1479(1):75-93.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₁₈O₆

[ Molecular Weight ]:
330.33

[ Exact Mass ]:
330.11000

[ PSA ]:
93.06000

[ LogP ]:
3.18720

Safety Information

[ Symbol ]:

GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H410

[ Precautionary Statements ]:
P273-P501

[ Hazard Codes ]:
N

[ Risk Phrases ]:
50/53

[ Safety Phrases ]:
60-61

[ RIDADR ]:
UN 3077 9 / PGIII

Related Compounds

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