1,4,8,11-Tetraazacyclotetradecane
Names
[ CAS No. ]:
295-37-4
[ Name ]:
1,4,8,11-Tetraazacyclotetradecane
[Synonym ]:
JM 1498
EINECS 206-039-1
Cyclam
1,4,8,11-tetrazacyclotetradecane
14-crown-4N4
1,4,8,11-Tetraazacyclotetradecane
MFCD00005105
Chemical & Physical Properties
[ Density]:
0.9±0.1 g/cm3
[ Boiling Point ]:
321.1±10.0 °C at 760 mmHg
[ Melting Point ]:
184-186 °C(lit.)
[ Molecular Formula ]:
C10H24N4
[ Molecular Weight ]:
200.324
[ Flash Point ]:
153.0±14.1 °C
[ Exact Mass ]:
200.200104
[ PSA ]:
48.12000
[ LogP ]:
-0.97
[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C
[ Index of Refraction ]:
1.426
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XA5254800
- CHEMICAL NAME :
- 1,4,8,11-Tetraazacyclotetradecane
- CAS REGISTRY NUMBER :
- 295-37-4
- BEILSTEIN REFERENCE NO. :
- 0111811
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C10-H24-N4
- MOLECULAR WEIGHT :
- 200.38
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 371 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Skin and Appendages - primary irritation (after topical exposure)
- REFERENCE :
- CMSHAF Chemosphere. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1972- Volume(issue)/page/year: 17,839,1988
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
XA5254800
[ HS Code ]:
2933990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Inorg. Chem. 50(23) , 11868-76, (2011)
The nitric oxide reactivity of two copper(II) complexes, 1 and 2 with ligands L(1) and L(2), respectively, [L(1) = 5,5,7,12,12,14-hexamethyl-1,4,8,11-tetraazacyclotetradecane, L(2) = 5,5,7-trimethyl-[...
Zn(II)-cyclam based chromogenic sensors for recognition of ATP in aqueous solution under physiological conditions and their application as viable staining agents for microorganism.Inorg. Chem. 50(9) , 4162-70, (2011)
Two chromogenic complexes, L.Zn (where L is (E)-4-((4-(1,4,8,11-tetraazacyclotetradecan-1-ylsulfonyl)phenyl)diazenyl)-N,N-dimethylaniline) and its [2]pseudorotaxane form (α-CD.L.Zn), were found to bin...
A reversible nanoswitch as an ON-OFF photocatalyst.Chem. Commun. (Camb.) 48(96) , 11730-2, (2012)
The two states of a new nanomechanical switch were quantitatively and reversibly populated in several subsequent switching cycles using either Cu(+) or cyclam as chemical inputs. State II was demonstr...