2’-Deoxy-2’-fluoro-5-methyl-4’-thio-a-D-arabino uridine

Names

[ CAS No. ]:
294868-24-9

[ Name ]:
2’-Deoxy-2’-fluoro-5-methyl-4’-thio-a-D-arabino uridine

Biological Activity

[Description]:

2’-Deoxy-2’-fluoro-5-methyl-4’-thio-a-D-arabino uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Molecular Formula ]:
C10H13FN2O4S

[ Molecular Weight ]:
276.28

Related Compounds