<Suppliers Price>

Tabersonine hydrochloride

Names

[ CAS No. ]:
29479-00-3

[ Name ]:
Tabersonine hydrochloride

[Synonym ]:
ent-2,3,6,7-Tetradehydro-aspidospermidin-3-carbonsaeure-methylester, Hydrochlorid
ent-2,3,6,7-tetradehydro-aspidospermidine-3-carboxylic acid methyl ester, hydrochloride

Biological Activity

[Description]:

Tabersonine is an indole alkaloid mainly isolated from Catharanthus roseus. Tabersonine disrupts Aβ(1-42) aggregation and ameliorates Aβ aggregate-induced cytotoxicity. Tabersonine has anti-inflammatory activities and is a potential therapeutic candidate for the treatment of ALI/ARDS[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology
Research Areas >> Neurological Disease

[References]

[1]. Zhang D, et al. Tabersonine attenuates lipopolysaccharide-induced acute lung injury via suppressing TRAF6 ubiquitination. Biochem Pharmacol. 2018 Aug;154:183-192.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H25ClN2O2

[ Molecular Weight ]:
372.88800

[ Exact Mass ]:
372.16000

[ PSA ]:
41.57000

[ LogP ]:
4.09910

[ Storage condition ]:
-20℃

Related Compounds