Diethyl Cyanophosphonate
Names
[ CAS No. ]:
2942-58-7
[ Name ]:
Diethyl Cyanophosphonate
[Synonym ]:
diethylphosphoric cyanide
Diethyl cyanophosphosphonate
Cyanophosphonic Acid Diethyl Ester
Diethylcyanophosphonate
Diethylcyanophosphate
diethoxyphosphoryl cyanide
Diethyl phosphorocyanidate
Diethyl phosphoryl cyanide
MFCD00010256
Diethyl cyanidophosphate
Diethylphosphorocyanidate
Phosphorocyanidic acid,diethyl ester
EINECS 220-936-5
Phosphorocyanidic acid, diethyl ester
Diethyl Cyanophosphonate
DEPC,Diethyl phosphoryl cyanide
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
214.2±9.0 °C at 760 mmHg
[ Molecular Formula ]:
C5H10NO3P
[ Molecular Weight ]:
163.112
[ Flash Point ]:
80.6±0.0 °C
[ Exact Mass ]:
163.039825
[ PSA ]:
69.13000
[ LogP ]:
0.04
[ Vapour Pressure ]:
0.2±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.416
[ Storage condition ]:
2-8°C
[ Water Solubility ]:
DECOMPOSES
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TD2500000
- CHEMICAL NAME :
- Phosphorocyanidic acid, O,O-diethyl ester
- CAS REGISTRY NUMBER :
- 2942-58-7
- BEILSTEIN REFERENCE NO. :
- 1768938
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C5-H10-N-O3-P
- MOLECULAR WEIGHT :
- 163.13
- WISWESSER LINE NOTATION :
- NCPO&O2&O2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1400 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PAREAQ Pharmacological Reviews. (Williams & Wilkins, 428 E. Preston St., Baltimore, MD 21202) V.1- 1949- Volume(issue)/page/year: 11,636,1959
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 25 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- JCSOA9 Journal of the Chemical Society. (London, UK) 1926-65. For publisher information, see JCPRB4. Volume(issue)/page/year: -,699,1948
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 4 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- JCSOA9 Journal of the Chemical Society. (London, UK) 1926-65. For publisher information, see JCPRB4. Volume(issue)/page/year: -,699,1948 *** REVIEWS *** TOXICOLOGY REVIEW CHREAY Chemical Reviews. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1924- Volume(issue)/page/year: 48,225,1951
Safety Information
[ Symbol ]:
GHS05, GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H300 + H310 + H330-H314
[ Supplemental HS ]:
Contact with acids liberates very toxic gas.
[ Precautionary Statements ]:
P260-P264-P280-P284-P301 + P310-P302 + P350
[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
T+:Verytoxic;C:Corrosive;
[ Risk Phrases ]:
R26/27/28;R32;R34
[ Safety Phrases ]:
S26-S36-S45-S50A-S36/37/39-S28A
[ RIDADR ]:
UN 2922 8/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
TD2500000
[ Packaging Group ]:
II
[ Hazard Class ]:
8
[ HS Code ]:
2931900090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2931900090
[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%
Articles
Yakugaku Zasshi 108(12) , 1115-28, (1988)
Amino acids and peptides. XXXI. Phosphorus in organic synthesis. XVIII. Synthesis of porcine motilin by the solid-phase method using diphenyl phosphorazidate(DPPA) and diethyl phosphorocyanidate(DEPC).
Chem. Pharm. Bull. 28(11) , 3347-56, (1980)
Precolumn fluorescence tagging reagent for carboxylic acids in high-performance liquid chromatography: 4-substituted-7-aminoalkylamino-2,1,3-benzoxadiazoles.
J. Chromatogr. A. 588 , 61, (1991)
Four new 2,1,3-benzoxadiazole amine reagents having different functional groups at the 4- and 7-positions, [4-nitro-7-N-piperazino-2,1,3-benzoxadiazole (NBD-PZ), 4-(N,N-dimethylaminosulphonyl)-7-N-pip...