PLK1-IN-7

Names

[ CAS No. ]:
2938910-96-2

[ Name ]:
PLK1-IN-7

Biological Activity

[Description]:

PLK1-IN-7 (compound 30e) is a potent PLK1 inhibitor, with an IC50 of 0.66 nM. PLK1-IN-7 exhibits antiproliferative and antitumor activities[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Polo-like Kinase (PLK)

[References]

[1]. Lu J, et, al. Design, synthesis, and biological evaluation of novel molecules as potent inhibitors of PLK1. Bioorg Chem. 2023 Oct:139:106711.  

Chemical & Physical Properties

[ Molecular Formula ]:
C24H24F4N8O2

[ Molecular Weight ]:
532.49

Related Compounds

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