2,4-DIISOPROPYLPHENOL

Names

[ Name ]:
2,4-DIISOPROPYLPHENOL

[Synonym ]:
EINECS 220-906-1
MFCD01707536
2,4-di(propan-2-yl)phenol
2,4-DIISOPROPYLPHENOL
Phenol, 2,4-bis(1-methylethyl)-

Biological Activity

[Description]:

2,4-Diisopropylphenol is one of the most widely accepted chemical agent used for induction of anesthesia[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[References]

[1]. Yasa Sathyam Reddy , et al. Study on Synthesis, Characterization and Antiproliferative Activity of Novel Diisopropylphenyl Esters of Selected Fatty Acids. J Oleo Sci. 2016;65(1):81-9.

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
244.0±9.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₂H₁₈O

[ Molecular Weight ]:
178.271

[ Flash Point ]:
109.6±7.2 °C

[ Exact Mass ]:
178.135757

[ PSA ]:
20.23000

[ LogP ]:
4.16

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.513

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SL0800000

CHEMICAL NAME :: Phenol, 2,4-diisopropyl-

CAS REGISTRY NUMBER :: 2934-05-6

BEILSTEIN REFERENCE NO. :: 1864621

LAST UPDATED :: 199710

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C12-H18-O

MOLECULAR WEIGHT :: 178.30

WISWESSER LINE NOTATION :: QR BY1&1 DY1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 120 mg/kg

TOXIC EFFECTS :: Behavioral - sleep

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,1350,1980

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
SL0800000

[ HS Code ]:
2907199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2907199090

[ Summary ]:
2907199090 other monophenols VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Synthesis and characterization of novel PUFA esters exhibiting potential anticancer activities: an in vitro study.

Eur. J. Med. Chem. 46 , 4878-86, (2011)

Polyunsaturated fatty acids (PUFAs) have been reported to play a regulatory role in tumour growth progression. In the present study, we have synthesized ester derivatives of two important PUFA viz., l...

Toxicological properties of thio- and alkylphenols causing flavor tainting in fish from the upper Wisconsin River.

J. Environ. Sci. Health B 24(4) , 349-60, (1989)

EC50 Microtox (5 min, 25 degrees C) assay values for 2-isopropylphenol, 3-isopropylphenol, 4-isopropylphenol, 2,4-diisopropylphenol, 2,5-diisopropylphenol 2,6-diisopropylphenol, 3,5-diisopropylphenol,...

Organic Reactions with Boron Fluoride. V. The Rearrangement of Isopropylphenol, o-, m-and p-Cresyl Ethers. Sowa FJ, et al.

J. Am. Chem. Soc. 55(8) , 3402-3407., (1933)