USP1-IN-5

Names

[ CAS No. ]:
2925547-94-8

[ Name ]:
USP1-IN-5

Biological Activity

[Description]:

USP1-IN-5 (compound 10) is a USP1 inhibitor (IC50<50 nM). USP1-IN-5 also inhibits MDA-MB-436 cells with IC50 <50 nM[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Deubiquitinase

[Target]

IC50: <50 nM (USP1)[1]

[References]

[1]. Wu J, et al. Preparation of heteroaromatic compounds as small molecule inhibitors of ubiquitin specific protease 1 (USP1) and uses thereof. World Intellectual Property Organization, WO2023083285 A1. 2023-05-19.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₇H₂₃F₃N₈O

[ Molecular Weight ]:
532.52

Related Compounds

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