UCL-TRO-1938

Names

[ CAS No. ]:
2919575-27-0

[ Name ]:
UCL-TRO-1938

Biological Activity

[Description]:

UCL-TRO-1938 is a potent allosteric activator of PI3Kα with an EC50 value of approximately 60 μM. UCL-TRO-1938 can induce cell proliferation and has cardioprotective and neural regeneration effects[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PI3K/Akt/mTOR >> PI3K

[References]

[1]. Grace Q Gong, et al. A small-molecule PI3Kα activator for cardioprotection and neuroregeneration. Nature. 2023 Jun;618(7963):159-168.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₇H₃₂N₆O

[ Molecular Weight ]:
456.58

Related Compounds

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