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Shegansu B

Names

[ CAS No. ]:
291535-65-4

[ Name ]:
Shegansu B

[Synonym ]:
5-{(E)-2-[(2S,3S)-3-(3,5-Dihydroxyphenyl)-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-2,3-dihydro-1-benzofuran-5-yl]vinyl}-1,3-benzenediol
1,3-Benzenediol, 5-[(E)-2-[(2S,3S)-3-(3,5-dihydroxyphenyl)-2,3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-5-benzofuranyl]ethenyl]-

Biological Activity

[Description]:

Shegansu B is an inhibitor of IL-1β. Shegansu B 6 inhibits IL-1β expression on LPS-induced THP-1 cells with 64.74% inhibition. Shegansu B has anti-inflammatory activity[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> Interleukin Related
Research Areas >> Inflammation/Immunology

[References]

[1]. Tian LW, et al. A new dimeric stilbene from the lianas of Gnetum parvifolium. Nat Prod Res. 2017 Jul;31(13):1495-1500.  

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
725.9±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C30H26O8

[ Molecular Weight ]:
514.523

[ Flash Point ]:
392.8±32.9 °C

[ Exact Mass ]:
514.162781

[ LogP ]:
4.00

[ Vapour Pressure ]:
0.0±2.4 mmHg at 25°C

[ Index of Refraction ]:
1.732

Related Compounds