Reserpic Acid Methyl Ester

Names

[ Name ]:
Reserpic Acid Methyl Ester

[Synonym ]:
Reserpic acid, methyl ester
Methyl reserpate
EINECS 220-792-3

Biological Activity

[Description]:

Methyl reserpate (NSC 81464) is a Yohimbine (HY-12715) type alkaloid, that can be isolated from Rauwolfia vomitoria roots and leaves[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Iwu M M, et al. Stem Bark Alkaloids of Rauwolfia vomitoria. Planta Medica, 1982, 45(2):105-111.

Chemical & Physical Properties

[ Density]:
1.32g/cm3

[ Boiling Point ]:
587.8ºC at 760 mmHg

[ Molecular Formula ]:
C₂₃H₃₀N₂O₅

[ Molecular Weight ]:
414.49500

[ Flash Point ]:
309.3ºC

[ Exact Mass ]:
414.21500

[ PSA ]:
84.02000

[ LogP ]:
2.21850

[ Vapour Pressure ]:
1.17E-14mmHg at 25°C

[ Index of Refraction ]:
1.634

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ZF9890000

CHEMICAL NAME :: 3-beta,20-alpha-Yohimban-16-beta-carboxylic acid, 18-beta-hydroxy-11,17-alpha-dimethoxy-, methyl ester

CAS REGISTRY NUMBER :: 2901-66-8

LAST UPDATED :: 198910

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C23-H30-N2-O5

MOLECULAR WEIGHT :: 414.55

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 479 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FRXXBL French Demande Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2390163

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 210 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FRXXBL French Demande Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2390163

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 48 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FRXXBL French Demande Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2390163

Safety Information

[ RIDADR ]:
UN 1544

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

Precursor & DownStream

Precursor

DownStream

Related Compounds

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