BDM91270

Names

[ CAS No. ]:
2892824-11-0

[ Name ]:
BDM91270

Biological Activity

[Description]:

BDM91270 (compound 29) is an E. coli AcrAB-TolC efflux pump inhibitor with an EC90 of 0.6 μM for wild-type E. coli AcrB. BDM91270 can be used in the study of Escherichia coli drug resistance[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[Target]

EC90: 0.6 μM (AcrB)[1].


[References]

[1]. Compagne N, et al. Optimization of pyridylpiperazine-based inhibitors of the Escherichia coli AcrAB-TolC efflux pump. Eur J Med Chem. 2023 Jul 7;259:115630.  

Chemical & Physical Properties

[ Molecular Formula ]:
C17H21Cl3N4O2

[ Molecular Weight ]:
419.73

Related Compounds

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