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N-Desalkylflurazepam

Names

[ CAS No. ]:
2886-65-9

[ Name ]:
N-Desalkylflurazepam

[Synonym ]:
Norfludiazepam
N-Desalkylflurazepam
Ro 5-3367
Norflutoprazepam
7-Chloro-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2-ol
2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(2-fluorophenyl)-1,3-dihydro-
7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
7-chloro-1,3-dihydro-5-(2-fluorophenyl)-2H-1,4-benzodiazepin-2-one
2H-1,4-BENZODIAZEPIN-2-ONE,1,3-DIHYDRO-7-CHLORO-5-(2-FLUOROPHENYL)
EINECS 220-748-3
5-(2-Fluorophenyl)-7-chloro-1,4-benzodiazepin-2-one
Dealkylflurazepam
nor-Flurazepam
MFCD00083443
CM 7116
7-Chloro-5-(2-fluorophenyl)-1H-benzo[e][1,4]diazepin-2(3H)-one
N-DESALKYL-2-OXOQUAZEPAM
7-chloro-5-(2-fluorophenyl)-1,3-dihydro-1,4-benzodiazepin-2(2H)-one
Descarbethoxyloflazepate
3H-1,4-Benzodiazepin-2-ol, 7-chloro-5-(2-fluorophenyl)-
7-chloro-5-(2-fluorophenyl)-1,3-dihydrobenzo[e][1,4]diazepin-2-one

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
463.5±55.0 °C at 760 mmHg

[ Melting Point ]:
204-206°C

[ Molecular Formula ]:
C15H10ClFN2O

[ Molecular Weight ]:
288.704

[ Flash Point ]:
234.1±31.5 °C

[ Exact Mass ]:
288.046570

[ PSA ]:
41.46000

[ LogP ]:
2.40

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.648

[ Storage condition ]:
-20°C Freezer

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DF2370100
CHEMICAL NAME :
2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-5-(2-fluorophenyl)-
CAS REGISTRY NUMBER :
2886-65-9
BEILSTEIN REFERENCE NO. :
0754061
LAST UPDATED :
199706
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C15-H10-Cl-F-N2-O
MOLECULAR WEIGHT :
288.72
WISWESSER LINE NOTATION :
T67 GMV JN IHJ CG KR BF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
26RAAN "Benzodinzenines," Garattini, S., et al., New York, Raven Press, 1973 Volume(issue)/page/year: -,46,1973

Safety Information

[ Symbol ]:

GHS02, GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H301 + H311 + H331-H370

[ Precautionary Statements ]:
P210-P260-P280-P301 + P310-P311

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
F,T

[ Risk Phrases ]:
11-23/24/25-39/23/24/25

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
DF2370100

[ HS Code ]:
2933990090

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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