Multicaulisin

Names

[ Name ]:
Multicaulisin

[Synonym ]:
6-[(1R,5S,6R)-6-(2,4-Dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-(4-methyl-3-penten-1-yl)-2-cyclohexen-1-yl]-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one
4H-1-Benzopyran-4-one, 6-[(1R,5S,6R)-6-(2,4-dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-(4-methyl-3-penten-1-yl)-2-cyclohexen-1-yl]-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-

Biological Activity

[Description]:

Multicaulisin, a new Diels-Alder type adduct from Morus multicaulis roots, potently effects against Staphylococcus aureus (MRSA) isolates. Multicaulisin is an antibacterial drug and has the potential for MRSA infections research[1][2].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Multicaulisin potently effects against MRSA isolates with minimal inhibitory concentrations (MICs)/ minimal bactericidal concentrations (MBCs) at 2-8/16-128 mg/L[1].

[References]

[1]. Guo-Ying Zuo, et al. Potent anti-MRSA activity and synergism with aminoglycosides by flavonoid derivatives from the root barks of Morus alba, a traditional Chinese medicine. Medicinal Chemistry Research volume 28, pages1547-1556(2019)

[2]. F Ferrari, et al. Multicaulisin, a new Diels-Alder type adduct from Morus multicaulis. Fitoterapia. 2000 Apr;71(2):213-5.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
972.4±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₄₀H₃₆O₁₁

[ Molecular Weight ]:
692.707

[ Flash Point ]:
303.8±27.8 °C

[ Exact Mass ]:
692.225769

[ LogP ]:
7.25

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.710

Related Compounds

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