HHS-0701

Names

[ CAS No. ]:
2851993-91-2

[ Name ]:
HHS-0701

Biological Activity

[Description]:

HHS-0701, a sulfur-triazole exchange (SuTEx) ligand, is a potent tyrosine-reactive prostaglandin reductase 2 (PTGR2) inhibitor. HHS-0701 blocks PTGR2 metabolism of the lipid substrate 15-Keto-PGE2[1].

[Related Catalog]:

Research Areas >> Endocrinology

Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor

[In Vitro]

HHS-0701 (0.1, 0.25, 0.5, 1, 2.5, 5, 10, 25 μM; 2 小时) 在处理重组 PTGR2 过表达 HEK293T 细胞时导致浓度依赖性探针标记阻断[1] .

[References]

[1]. Emmanuel K Toroitich, et al.Discovery of a Cell-Active SuTEx Ligand of Prostaglandin Reductase 2. Chembiochem. 2021 Jun 15;22(12):2134-2139.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₂₀N₄O₃S

[ Molecular Weight ]:
396.46

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.