2851993-91-2

2851993-91-2 structure
2851993-91-2 structure
  • Name: HHS-0701
  • Chemical Name: HHS-0701
  • CAS Number: 2851993-91-2
  • Molecular Formula: C20H20N4O3S
  • Molecular Weight: 396.46
  • Catalog: Signaling Pathways GPCR/G Protein Prostaglandin Receptor
  • Create Date: 2023-04-27 11:43:30
  • Modify Date: 2024-01-31 15:40:29
  • HHS-0701, a sulfur-triazole exchange (SuTEx) ligand, is a potent tyrosine-reactive prostaglandin reductase 2 (PTGR2) inhibitor. HHS-0701 blocks PTGR2 metabolism of the lipid substrate 15-Keto-PGE2[1].

Name HHS-0701
Description HHS-0701, a sulfur-triazole exchange (SuTEx) ligand, is a potent tyrosine-reactive prostaglandin reductase 2 (PTGR2) inhibitor. HHS-0701 blocks PTGR2 metabolism of the lipid substrate 15-Keto-PGE2[1].
Related Catalog
In Vitro HHS-0701 (0.1, 0.25, 0.5, 1, 2.5, 5, 10, 25 μM; 2 小时) 在处理重组 PTGR2 过表达 HEK293T 细胞时导致浓度依赖性探针标记阻断[1] .
References

[1]. Emmanuel K Toroitich, et al.Discovery of a Cell-Active SuTEx Ligand of Prostaglandin Reductase 2. Chembiochem. 2021 Jun 15;22(12):2134-2139.  

Molecular Formula C20H20N4O3S
Molecular Weight 396.46
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