5'-chloro-2'-hydroxy-4'-methylacetophenone

Names

[ Name ]:
5'-chloro-2'-hydroxy-4'-methylacetophenone

[Synonym ]:
2-Acetyl-4-chloro-5-methylphenol
2-hydroxy-4-methyl-5-chloroacetophenone
MFCD00191920
2-hydroxy-5-chloro-4-methylacetophenone
4-Acetyl-2-chloro-5-hydroxytoluene
4-methyl-5-chloro-2-hydroxyacetophenone
5'-Chloro-2'-hydroxy-4'-methylacetophenone
5-chloro-4-methyl-2-hydroxyacetophenone

Chemical & Physical Properties

[ Density]:
1.25g/cm3

[ Boiling Point ]:
137 °C / 15mmHg

[ Melting Point ]:
70-73 °C(lit.)

[ Molecular Formula ]:
C₉H₉ClO₂

[ Molecular Weight ]:
184.62000

[ Flash Point ]:
132.2ºC

[ Exact Mass ]:
184.02900

[ PSA ]:
37.30000

[ LogP ]:
2.55660

[ Vapour Pressure ]:
0.000889mmHg at 25°C

[ Index of Refraction ]:
1.562

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2914700090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914700090

[ Summary ]:
HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

Articles

Synthesis of some new 1,3,5-trisubstituted pyrazolines bearing benzene sulfonamide as anticancer and anti-inflammatory agents.

Bioorg. Med. Chem. Lett. 21(14) , 4301-5, (2011)

Thirteen new 2-pyrazoline derivatives bearing benzenesulfonamide moiety (2a-m) were synthesized by condensing appropriate chalcones with 4-hydrazinonbenzenesulfonamide hydrochloride and tested for ant...

A Highly Sensitive and Selective Spectrophotometric Determination of Vanadium (V) Using 6-Chloro-3-hydroxy-7-methyl-2-(2-thienyl)-4H-chromen-4-one. Agnihotri N, et al.

Anal. Sci. 15(12) , 1261-64, (1999)

Pyridinium iodochloride: An efficient reagent for iodination of hydroxylated aromatic ketones and aldehydes. Khansole SV, et al.

J. Chin. Chem. Soc. 55(4) , 871-74, (2008)