Anti-infective agent 7

Names

[ Name ]:
Anti-infective agent 7

Biological Activity

[Description]:

Anti-infective agent 7 is a potent anti-infectious agent. Anti-infective agent 7 has anti-infection activity against P. falciparum (IC50=2.5 μM) and M. tuberculosis (MIC=9 μM)[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Anti-infective agent 7 (compound 17) is less cytotoxic with a CC50 value of 86 μM in macrophage RAW 264.7 cells and consequently a SI higher than 34 for Leishmania parasites[1].

[References]

[1]. Koumpoura CL, et, al. Design of Anti-infectious Agents from Lawsone in a Three-Component Reaction with Aldehydes and Isocyanides. ACS Omega. 2022 Oct 3;7(40):35635-35655.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₈H₃₀N₂O₃

[ Molecular Weight ]:
442.55

Related Compounds

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