RTIOXA-43

Names

[ CAS No. ]:
2832067-72-6

[ Name ]:
RTIOXA-43

Biological Activity

[Description]:

RTIOXA-43 is a orexin receptor agonist with EC50s of 24 nM and 24 nM for OX2 and OX1 receptors, respectively[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Orexin Receptor (OX Receptor)
Research Areas >> Neurological Disease

[Target]

OX1:24 nM (EC50)

OX2:24 nM (EC50)


[References]

[1]. Yanan Zhang, et al. Arylsulfoxamides as orexin receptor agonists. WO2022187231A1.

[2]. Kotz, Catherine, et al. Small Molecule Orexin Agonists Enhance Physical Activity, Cognition and Sleep Quality in Aged Mice. Obesity; Silver Spring Vol. 29, (Dec 2021): 163.

Chemical & Physical Properties

[ Molecular Formula ]:
C37H37N5O5S

[ Molecular Weight ]:
663.79

Related Compounds