Poly(styrene sulfonic acid)

Names

[ Name ]:
Poly(styrene sulfonic acid)

[Synonym ]:
MFCD00165973
Tolevamer
Poly(styrene sulfonic acid)

Biological Activity

[Description]:

Polystyrene forms Polystyrene microplastics (PS-MPs), a hazardous material with potential toxicity. Polystyrene microplastics is harm to zebrafish heart and induces male reproductive toxicity in mice[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Polystyrene results 0.5 μm, 4 μm, and 10 μm PS-MPs entering into three kinds of testicular cells (GC-1 cell line) in vitro[2].

[In Vivo]

Polystyrene (PS-MPs, particle sizes 3-12 µm; p.o.; 21 d) shows adverse effect on zebrafish activity and oxidative stress, metabolic changes and contraction parameters in the heart tissue[1]. Polystyrene (PS-MPs, particle sizes of 4 μm and 10 μm; p.o.; 24 h) resultsPS-MPs accumulated in the testis of mice, and (PS-MPs, particle sizes of 4 μm and 10 μm; p.o.; 28 d) induces spermatogenic cells abscissed and arranged disorderly, and multinucleated gonocytes occurred in the seminiferous tubule[2]. Polystyrene, (PS-MPs, particle sizes of 0.5 μm, 4 μm and 10 μm; p.o.; 28 d) induces testicular inflammation and the disruption of blood-testis barrier[2].

Chemical & Physical Properties

[ Density]:
1.11 g/mL at 25 °C

[ Boiling Point ]:
100°C

[ Melting Point ]:
1°C

[ Molecular Formula ]:
C₈H₈O₃S

[ Molecular Weight ]:
184.21200

[ Exact Mass ]:
184.01900

[ PSA ]:
62.75000

[ LogP ]:
2.66760

[ Appearance of Characters ]:
Liquid | Amber

[ Index of Refraction ]:
n20/D 1.3718

[ Water Solubility ]:
H2O: soluble

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C

[ Risk Phrases ]:
34-35

[ Safety Phrases ]:
23-26-36/37/39-45

[ RIDADR ]:
UN 2586 8/PG 3

[ WGK Germany ]:
-

Articles

Surface functionality as a means to impact polymer nanoparticle size and structure.

Langmuir 29(12) , 4092-5, (2013)

When polymeric nanoparticles (NPs) are formed by nanoprecipitation, which is a nucleation-growth process, the control over size requires changing the polymer concentration or solvent composition. Here...

Gastrointestinal adverse events with sodium polystyrene sulfonate (Kayexalate) use: a systematic review.

Am. J. Med. 126(3) , 264.e9-24, (2013)

Sodium polystyrene sulfonate (Kayexalate; Sanofi-Aventis, Paris, France) is a cation-exchange resin routinely used in the management of hyperkalemia. However, its use has been associated with colonic ...

Divalent-anion salt effects in polyelectrolyte multilayer depositions.

Langmuir 28(45) , 15831-43, (2012)

We systematically investigate the effects of divalent anions on the assembly of polyelectrolyte multilayers by fabricating polystyrene sulfonate (PSS)/polyallylamine hydrochloride (PAH) multilayer fil...