MRV03-070

Names

[ CAS No. ]:
2797066-29-4

[ Name ]:
MRV03-070

Biological Activity

[Description]:

MRV03-070 is an inhibitor of colibactin-activating peptidase ClbP with an IC50 value of 69 nM, acts like biosynthetic precursor precolibactin[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

MRV03-070 (compound 4) (0.01 nM-0.1 mM for 1 h) inhibits ClbP acitivity with IC50s of 69 nM and 27 nM, respectively, measured both in vitro and in E. coli BL21 overexpressing ClbP[1].

Chemical & Physical Properties

[ Molecular Formula ]:
C10H13BN2O4

[ Molecular Weight ]:
236.03

Related Compounds