Tolindate

Names

[ CAS No. ]:
27877-51-6

[ Name ]:
Tolindate

[Synonym ]:
Tolindat
Tolindate (USAN/INN)
Tolindatum
Tolindata
TOLINDATE
Tolindato

[Description]:

Tolindate is a potent PXR agonist with an EC50 value of 8.3 µM. Tolindate shows antifungal activity[1][2].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

Research Areas >> Metabolic Disease

[In Vitro]

Tolindate (0-100 µM; 24 h) with the presence of SPA70 (0.5, 7.5 µM) shows significantly induces CYP3A4 in hPXR HepG2 cells[1].

[ Density]:
1.208g/cm3

[ Boiling Point ]:
425.1ºC at 760mmHg

[ Molecular Formula ]:
C₁₈H₁₉NOS

[ Molecular Weight ]:
297.41500

[ Flash Point ]:
210.9ºC

[ Exact Mass ]:
297.11900

[ PSA ]:
44.56000

[ LogP ]:
4.28380

[ Vapour Pressure ]:
1.96E-07mmHg at 25°C

[ Index of Refraction ]:
1.662

[ HS Code ]:
2930909090

[ HS Code ]: 2930909090

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%