27877-51-6
27877-51-6 structure
- Name: Tolindate
- Chemical Name: O-(2,3-dihydro-1H-inden-5-yl) N-methyl-N-(3-methylphenyl)carbamothioate
- CAS Number: 27877-51-6
- Molecular Formula: C18H19NOS
- Molecular Weight: 297.41500
- Catalog: Signaling Pathways Anti-infection Fungal
- Create Date: 2017-07-08 23:16:42
- Modify Date: 2024-01-25 05:58:42
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Tolindate is a potent PXR agonist with an EC50 value of 8.3 µM. Tolindate shows antifungal activity[1][2].
| Name | O-(2,3-dihydro-1H-inden-5-yl) N-methyl-N-(3-methylphenyl)carbamothioate |
|---|---|
| Synonyms |
Tolindat
Tolindate (USAN/INN) Tolindatum Tolindata TOLINDATE Tolindato |
| Description | Tolindate is a potent PXR agonist with an EC50 value of 8.3 µM. Tolindate shows antifungal activity[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | Tolindate (0-100 µM; 24 h) with the presence of SPA70 (0.5, 7.5 µM) shows significantly induces CYP3A4 in hPXR HepG2 cells[1]. |
| Density | 1.208g/cm3 |
|---|---|
| Boiling Point | 425.1ºC at 760mmHg |
| Molecular Formula | C18H19NOS |
| Molecular Weight | 297.41500 |
| Flash Point | 210.9ºC |
| Exact Mass | 297.11900 |
| PSA | 44.56000 |
| LogP | 4.28380 |
| Vapour Pressure | 1.96E-07mmHg at 25°C |
| Index of Refraction | 1.662 |
| HS Code | 2930909090 |
|---|
| HS Code | 2930909090 |
|---|---|
| Summary | 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |