Zharp2-1

Names

[ Name ]:
Zharp2-1

Biological Activity

[Description]:

Zharp2-1 is an oral effective RIPK2 inhibitor, highly associated with inflammatory bowel disease (IBD). Zharp2-1 blocker muramyl dipeptide (MDP) induces growth of mononuclear cells and induces inflammatory cell factor infection. Zharp2-1 attenuates MDP-induced small inguinal peritonitis, or ameliorates by DNBS-induced large inguinal conjunctivitis[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> RIP kinase

Research Areas >> Inflammation/Immunology

[Target]

RIPK2[1]

[References]

[1]. Lai Y, et al. Discovery of a novel RIPK2 inhibitor for the treatment of inflammatory bowel disease. Biochem Pharmacol. 2023 Aug;214:115647.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₁₈N₃O₂PS

[ Molecular Weight ]:
383.40

Related Compounds

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