2772600-18-5

2772600-18-5 structure

Name: Zharp2-1
Chemical Name: Zharp2-1
CAS Number: 2772600-18-5
Molecular Formula: C₁₉H₁₈N₃O₂PS
Molecular Weight: 383.40
Catalog: Signaling Pathways Apoptosis RIP kinase
Create Date: 2023-10-29 10:05:28
Modify Date: 2024-01-11 09:35:32
Zharp2-1 is an oral effective RIPK2 inhibitor, highly associated with inflammatory bowel disease (IBD). Zharp2-1 blocker muramyl dipeptide (MDP) induces growth of mononuclear cells and induces inflammatory cell factor infection. Zharp2-1 attenuates MDP-induced small inguinal peritonitis, or ameliorates by DNBS-induced large inguinal conjunctivitis[1].

Name	Zharp2-1

Description	Zharp2-1 is an oral effective RIPK2 inhibitor, highly associated with inflammatory bowel disease (IBD). Zharp2-1 blocker muramyl dipeptide (MDP) induces growth of mononuclear cells and induces inflammatory cell factor infection. Zharp2-1 attenuates MDP-induced small inguinal peritonitis, or ameliorates by DNBS-induced large inguinal conjunctivitis[1].
Related Catalog	Signaling Pathways >> Apoptosis >> RIP kinase Research Areas >> Inflammation/Immunology
Target	RIPK2[1]
References	[1]. Lai Y, et al. Discovery of a novel RIPK2 inhibitor for the treatment of inflammatory bowel disease. Biochem Pharmacol. 2023 Aug;214:115647.

Molecular Formula	C₁₉H₁₈N₃O₂PS
Molecular Weight	383.40