RMC-7977

Names

[ Name ]:
RMC-7977

Biological Activity

[Description]:

RMC-7977 is a reversible, tri-complex RAS inhibitor with broad spectrum activity for both mutant and wild-type (WT) KRAS, NRAS, and HRAS variants.RMC-7977 can lead to tumor regressions and was well tolerated in diverse RAS-addicted preclinical cancer models. RMC-7977 also can inhibit the growth of KRASG12C cancer models[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> GPCR/G Protein >> Ras

[References]

[1]. Singh M, et al. Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy. Research Square; 2023.

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₇H₆₀N₈O₆S

[ Molecular Weight ]:
865.09

Related Compounds

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