2765082-12-8

2765082-12-8 structure

Name: RMC-7977
Chemical Name: RMC-7977
CAS Number: 2765082-12-8
Molecular Formula: C₄₇H₆₀N₈O₆S
Molecular Weight: 865.09
Catalog: Signaling Pathways GPCR/G Protein Ras
Create Date: 2024-02-22 18:25:40
Modify Date: 2024-02-22 18:25:40
RMC-7977 is a reversible, tri-complex RAS inhibitor with broad spectrum activity for both mutant and wild-type (WT) KRAS, NRAS, and HRAS variants.RMC-7977 can lead to tumor regressions and was well tolerated in diverse RAS-addicted preclinical cancer models. RMC-7977 also can inhibit the growth of KRASG12C cancer models[1].

Name	RMC-7977

Description	RMC-7977 is a reversible, tri-complex RAS inhibitor with broad spectrum activity for both mutant and wild-type (WT) KRAS, NRAS, and HRAS variants.RMC-7977 can lead to tumor regressions and was well tolerated in diverse RAS-addicted preclinical cancer models. RMC-7977 also can inhibit the growth of KRASG12C cancer models[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Ras
References	[1]. Singh M, et al. Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy. Research Square; 2023.

Molecular Formula	C₄₇H₆₀N₈O₆S
Molecular Weight	865.09