Immuno modulator-1

Names

[ CAS No. ]:
2757469-20-6

[ Name ]:
Immuno modulator-1

Biological Activity

[Description]:

Immuno modulator-1 (compound 22) inhibits TNFα and IL-2 secretion in human peripheral blood mononuclear cells (hPBMC), with IC50 values of 4.7 and 26 nM, respectively. Immuno modulator-1 shows hERG potassium channel blocking effect, with Inhibitory percentage of 20% at 3 μM[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Immunology/Inflammation >> Interleukin Related
Research Areas >> Inflammation/Immunology
Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel

[Target]

IL-2


[References]

[1]. Chen Xiangyang, et al. Heterocyclic immunomodulator. Patent, WO2022007659A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C32H31FN6O4

[ Molecular Weight ]:
582.62

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.