Nav1.8-IN-2

Names

[ Name ]:
Nav1.8-IN-2

Biological Activity

[Description]:

Nav1.8-IN-2 (compound 35A) is a potent Nav1.8 inhibitor with an IC50 value of 0.4 nM. Nav1.8-IN-2 can be used for researching pain disorders, cough disorders, and acute and chronic itch disorders[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel

Research Areas >> Neurological Disease

[Target]

Nav1.8:0.4 nM (IC50)

[References]

[1]. Sabnis RW. 2-Oxooxazolidine-5-carboxamides as Nav1.8 Inhibitors for Treating Pain Disorders, Cough Disorders, and Acute and Chronic Itch Disorders. ACS Med Chem Lett. 2022;13(3):334-335. Published 2022 Mar 1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₁₃Cl₂F₃N₂O₃

[ Molecular Weight ]:
433.21

Related Compounds

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