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IGUANA-1

Names

[ CAS No. ]:
2756014-25-0

[ Name ]:
IGUANA-1

Biological Activity

[Description]:

IGUANA-1 is a potent inhibitor of ALDH1B1, which is a mitochondrial enzyme that promotes colorectal and pancreatic cancer. IGUANA-1 has significant inhibition against cancer cells[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Aldehyde Dehydrogenase (ALDH)
Research Areas >> Cancer

[Target]

ALDH1


[References]

[1]. Feng Z, et al. Targeting colorectal cancer with small-molecule inhibitors of ALDH1B1. Nat Chem Biol. 2022 Oct;18(10):1065-1075.  

Chemical & Physical Properties

[ Molecular Formula ]:
C27H26ClN3O4

[ Molecular Weight ]:
491.97


Related Compounds

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