1-Aminocyclohexanecarboxylic acid
Names
[ CAS No. ]:
2756-85-6
[ Name ]:
1-Aminocyclohexanecarboxylic acid
[Synonym ]:
1-amino-cyclohexane-1-carboxylic acid
Cyclohexanecarboxylic acid,1-amino
a-Aminocyclohexanecarboxylic acid
1-Aminocyclohexanecarboxylic acid
1-amino-1-cyclo-hexanecarboxylic acid
1-amino-1-cyclohexane carboxylic acid
Homocycloleucine
1-aminocyclohexane-1-carboxylic acid
1-amino-1-cyclohexylcarboxylic acid
1-amino-1-cyclohexanecarboxylic acid
MFCD00001487
Cyclohexanecarboxylic acid, 1-amino-
1-Amino-1-CyclohexanecarboxylicAcid
EINECS 220-411-0
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
272.3±23.0 °C at 760 mmHg
[ Melting Point ]:
>300 °C(lit.)
[ Molecular Formula ]:
C7H13NO2
[ Molecular Weight ]:
143.184
[ Flash Point ]:
118.5±22.6 °C
[ Exact Mass ]:
143.094635
[ PSA ]:
63.32000
[ LogP ]:
0.51
[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C
[ Index of Refraction ]:
1.509
[ Storage condition ]:
Store at RT.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GU8393000
- CHEMICAL NAME :
- Cyclohexanecarboxylic acid, 1-amino-
- CAS REGISTRY NUMBER :
- 2756-85-6
- BEILSTEIN REFERENCE NO. :
- 2355692
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C7-H13-N-O2
- MOLECULAR WEIGHT :
- 143.21
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 5,108,1960
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S22-S24/25-S37/39-S26
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
GU8393000
[ HS Code ]:
2922499990
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922499990
[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%
Articles
J. Med. Chem. 52 , 5093-107, (2009)
Retaining agonistic activity at the glycine coagonist site of the NMDA receptor in molecules derived from glycine or d-serine has proven to be difficult because in the vicinity of the alpha-amino acid...
Application of 1-aminocyclohexane carboxylic acid to protein nanostructure computer design.J. Chem. Inf. Model. 48(2) , 333-43, (2008)
Conformationally restricted amino acids are promising candidates to serve as basic pieces in redesigned protein motifs which constitute the basic modules in synthetic nanoconstructs. Here we study the...
Influence of 1-aminocyclohexane-1-carboxylic acid in position 2 or 3 of AVP and its analogues on their pharmacological properties.J. Pept. Res. 62(2) , 70-7, (2003)
In this study we describe the synthesis and some pharmacological properties of seven new analogues of arginine vasopressin (AVP) substituted in position 2 or 3 with 1-aminocyclohexane-1-carboxylic aci...