13,14-dihydro-15-keto PGF2a

Names

[ Name ]:
13,14-dihydro-15-keto PGF2a

[Synonym ]:
Prost-5-en-1-oic acid, 9,11-dihydroxy-15-oxo-, (5Z,9α,11α)-
13,14-DIHYDRO-15-KETO PROSTAGLANDIN F2ALPHA
13,14-dihydro-15-keto PGF2a
13,14-Dihydro-15-keto-pgf2α
Prostaglandin FM
13,14-Dihydro-15-ketoprostaglandin f
15-Keto-13,14-dihydro-pgf2alpha
13,14-Dihydro-15-oxoprostaglandin f
13,14-Dihydro-15-ketodinoprost
PGFM
(5Z,9α,11α)-9,11-Dihydroxy-15-oxoprost-5-en-1-oic acid
13,14-dihydro-15-keto-PGF2alpha

Biological Activity

[Description]:

13,14-Dihydro-15-keto PGF2a is an endogenous metabolite present in Blood that can be used for the research of Pregnancy[1][2].

[Related Catalog]:

Research Areas >> Others

[In Vitro]

Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1].

[References]

[1]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720.

[2]. The dynamic changes of several reproductive hormones during termination of early pregnancy by RU486 in combination with PG-05 in Chinese women. Adv Contracept. 1988 Dec;4(4):319-26.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
543.0±40.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₃₄O₅

[ Molecular Weight ]:
354.481

[ Flash Point ]:
296.2±23.8 °C

[ Exact Mass ]:
354.240631

[ PSA ]:
94.83000

[ LogP ]:
2.13

[ Vapour Pressure ]:
0.0±3.3 mmHg at 25°C

[ Index of Refraction ]:
1.512

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
20/21/22

[ Safety Phrases ]:
22-36

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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