PROTAC IRAK3 degrade-1

Names

[ CAS No. ]:
2712600-00-3

[ Name ]:
PROTAC IRAK3 degrade-1

Biological Activity

[Description]:

PROTAC IRAK3 degrade-1 is a potent and selective degrader of IRAK3 (IC50 = 5 nM).

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> PROTAC >> PROTAC

[References]

[1]. Degorce SL, et al. Discovery of Proteolysis-Targeting Chimera Molecules that Selectively Degrade the IRAK3 Pseudokinase. J Med Chem. 2020 Sep 24;63(18):10460-10473.

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₇H₆₃N₁₁O₆

[ Molecular Weight ]:
878.07

Related Compounds

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