8RK64

Names

[ CAS No. ]:
2705841-52-5

[ Name ]:
8RK64

Biological Activity

[Description]:

8RK64 is a covalent UCHL1 inhibitor (IC50: 0.32 μM)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Deubiquitinase

[Target]

IC50: 0.32 μM (UCHL1), 216 µM (UCHL3)[1]

[References]

[1]. Kooij R, et al. Small-Molecule Activity-Based Probe for Monitoring Ubiquitin C-Terminal Hydrolase L1 (UCHL1) Activity in Live Cells and Zebrafish Embryos. J Am Chem Soc. 2020 Sep 30;142(39):16825-16841.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄H₁₆N₈O₂S

[ Molecular Weight ]:
360.39

Related Compounds

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