Tyk2-IN-8

Names

[ CAS No. ]:
2704587-24-4

[ Name ]:
Tyk2-IN-8

Biological Activity

[Description]:

Tyk2-IN-8 (Compound 3) is a selective Tyk-2 inhibitor with an IC50 of 5.7 nM for TYK2-JH2. Tyk2-IN-8 inhibits JAK1-JH1 with IC50 of 3.0 nM. Tyk2-IN-8 can be used for the research of autoimmune disease[1].

[Related Catalog]:

Signaling Pathways >> JAK/STAT Signaling >> JAK
Signaling Pathways >> Epigenetics >> JAK
Signaling Pathways >> Stem Cell/Wnt >> JAK
Research Areas >> Inflammation/Immunology

[References]

[1]. Xiangyang Chen, et al. Heterocyclic compounds for inhibiting tyk2 activities. WO2021180072A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H19D3N8O3

[ Molecular Weight ]:
425.46

Related Compounds