Solasurine

Names

[ Name ]:
Solasurine

[Synonym ]:
(2R,3R,4S,5S,6R)-6-({[(2S,3S,4R,5R,6R)-3,5-Dihydroxy-2-methyl-6-{[(2S,4aR,4bS,5'R,6aS,6bR,7S,8R,9aS,10aS,10bS)-4a,5',6a,7-tetramethyl-1,2,3,4,4a,4b,5,6,6a,6b,7,9a,10,10a,10b,11-hexadecahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-8,2'-piperidin]-2-yl]oxy}tetrahydro-2H-pyran-4-yl]oxy}methyl)tetrahydro-2H-pyran-2,3,4,5-tetrol

Biological Activity

[Description]:

Solasurine is a steroidal alkaloid that can be isolated from Solanum surrattence. Solasurine can interact with the C3-like protease (SARS-CoV-2 main protease) amino acids Phe8, Pro9, Ile152, Tyr154, Pro293, Phe294, Val297, and Arg298[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Anamul Hasan, et al. Phytochemicals from Solanum surattense Burm.f. have high binding affinities for C-3 like main protease of COVID-19 (SARS-CoV-2).

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
851.9±65.0 °C at 760 mmHg

[ Melting Point ]:
228-230℃

[ Molecular Formula ]:
C₃₉H₆₃NO₁₁

[ Molecular Weight ]:
721.918

[ Flash Point ]:
469.0±34.3 °C

[ Exact Mass ]:
721.440125

[ PSA ]:
179.56000

[ LogP ]:
6.15

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.611

Safety Information

[ Hazard Codes ]:
Xi