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TNF-α-IN-6

Names

[ CAS No. ]:
2699704-20-4

[ Name ]:
TNF-α-IN-6

Biological Activity

[Description]:

TNF-α-IN-6 is an orally efficacious allosteric inhibitor of TNFα (KD = 6.8 nM).

[Related Catalog]:

Research Areas >> Inflammation/Immunology

[References]

[1]. Dietrich JD, et al. Development of Orally Efficacious Allosteric Inhibitors of TNFα via Fragment-Based Drug Design. J Med Chem. 2021 Jan 14;64(1):417-429.

Chemical & Physical Properties

[ Molecular Formula ]:
C26H25N9O2

[ Molecular Weight ]:
495.54

Related Compounds