1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt)

Names

[ Name ]:
1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt)

[Synonym ]:
UNII:T52TI8BMQ6
POPG Na,r
16:0-18:1 PG
POPG
1-Palmitoyl-2-oleoyl-phosphatidyl-glycerol sodium
9-Octadecenoic acid, (1R)-2-[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]-1-[[(1-oxohexadecyl)oxy]methyl]ethyl ester, sodium salt, (9Z)- (1:1)
Sodium 2,3-dihydroxypropyl (2R)-2-[(9Z)-9-octadecenoyloxy]-3-(palmitoyloxy)propyl phosphate
1-Palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)),sodium salt
POPG Na,l
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol,sodium salt
1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt)

Biological Activity

[Description]:

1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) sodium salt is a lipid molecule having one negative charge, which can interact with the positive charges of peptides[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Kim MR, et al. Co-Encapsulation and Co-Delivery of Peptide Drugs via Polymeric Nanoparticles. Polymers (Basel). 2019;11(2):288. Published 2019 Feb 8.

[2]. Kim MR, et al. Co-Encapsulation and Co-Delivery of Peptide Drugs via Polymeric Nanoparticles. Polymers (Basel). 2019;11(2):288. Published 2019 Feb 8.

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₀H₇₆NaO₁₀P

[ Molecular Weight ]:
770.989

[ Exact Mass ]:
770.507385

[ PSA ]:
161.46000

[ LogP ]:
10.88520

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Binding properties of antimicrobial agents to lipid membranes using surface plasmon resonance.

Biol. Pharm. Bull. 37(8) , 1383-9, (2014)

In the present study, we examined the interaction of antimicrobial agents with four model lipid membranes that mimicked mammalian cell membranes and Gram-positive and -negative bacterial membranes and...

Characterizing the structure of lipodisq nanoparticles for membrane protein spectroscopic studies.

Biochim. Biophys. Acta 1848(1 Pt B) , 329-33, (2015)

Membrane protein spectroscopic studies are challenging due to the difficulty introduced in preparing homogenous and functional hydrophobic proteins incorporated into a lipid bilayer system. Traditiona...

Detergent-type membrane fragmentation by MSI-78, MSI-367, MSI-594, and MSI-843 antimicrobial peptides and inhibition by cholesterol: a solid-state nuclear magnetic resonance study.

Biochemistry 54(10) , 1897-907, (2015)

Multidrug resistance against the existing antibiotics is becoming a global threat, and any potential drug that can be designed using cationic antimicrobial peptides (AMP) could be an alternate solutio...