PXYD3

Names

[ Name ]:
PXYD3

Biological Activity

[Description]:

PXYD3 is a ribosomal protein S1 (RpsA) antagonist with Kds of 5.66 and 6.91 μM for RpsA-CTD and RpsA-CTD Δ438A, respectively. RpsA plays an important role in the trans-translation process of Mycobacterium Tuberculosis (Mtb)[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[Target]

Kd: 5.66 μM (RpsA-CTD), 6.91 μM (RpsA-CTD Δ438A)[1]

[References]

[1]. Yazhuang Dai, et al. Discovery and evaluation of new compounds targeting ribosomal protein S1 in antibiotic-resistant Mycobacterium Tuberculosis. Eur J Med Chem. 2020 Jun 15;196:112317.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₂₁NO₅

[ Molecular Weight ]:
415.44

Related Compounds

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