Myoseverin

Names

[ Name ]:
Myoseverin

[Synonym ]:
9H-Purine-2,6-diamine, N,N-bis[(4-methoxyphenyl)methyl]-9-(1-methylethyl)-
9-Isopropyl-N,N'-bis(4-methoxybenzyl)-9H-purine-2,6-diamine
myoseverin
n,n'-bis(4-methoxybenzyl)-9-(propan-2-yl)-9h-purine-2,6-diamine
9-Isoproyl-N2,N6-bis-(4-methoxybenxyl)-9H-purine-2,6-diamine

Biological Activity

[Description]:

Myoseverina, a microtubule-binding molecule, induces the reversible fission of multinucleated myotubes into mononucleated fragments. Myoseverina affects the expression of a variety of growth factor, immunomodulatory, extracellular matrix-remodeling, and stress response genes, consistent with the activation of pathways involved in wound healing and tissue regeneration[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin

[References]

[1]. Rosania GR, et al. Myoseverin, a microtubule-binding molecule with novel cellular effects. Nat Biotechnol. 2000;18(3):304-308.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
661.3±65.0 °C at 760 mmHg

[ Melting Point ]:
108 °C

[ Molecular Formula ]:
C₂₄H₂₈N₆O₂

[ Molecular Weight ]:
432.518

[ Flash Point ]:
353.7±34.3 °C

[ Exact Mass ]:
432.227386

[ PSA ]:
86.12000

[ LogP ]:
3.04

[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C

[ Index of Refraction ]:
1.632

MSDS

Click to get detail MSDS

Safety Information

[ WGK Germany ]:
3

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.