WNY1613

Names

[ CAS No. ]:
2650546-39-5

[ Name ]:
WNY1613

Biological Activity

[Description]:

WNY1613 is a potent and selective PI3Kδ inhibitor with piperazinone-containing purine scaffold. WNY1613 induces cancer cell apoptosis and inhibits the phosphorylation of PI3K downstream components in NHL cell lines. WNY1613 exhibits anti-NHL activity in vitro and in vivo[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer
Signaling Pathways >> PI3K/Akt/mTOR >> PI3K

[References]

[1]. Zuo WQ, et al. Identification of a potent and selective phosphatidylinositol 3-kinase δ inhibitor for the treatment of non-Hodgkin's lymphoma. Bioorg Chem. 2020;105:104344.

Chemical & Physical Properties

[ Molecular Formula ]:
C29H35N9O3

[ Molecular Weight ]:
557.65

Related Compounds

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