CIAC001

Names

[ Name ]:
CIAC001

Biological Activity

[Description]:

CIAC001 is a Pyruvate Kinase PKM2 inhibitor with anti-neuroinflammatory activity. CIAC001 inhibits LPS-induced proinflammatory nitric oxide (NO) production and protects immunologically active BV-2 cells (IC50=2.5 μM). CIAC001 also has anti-neuroinflammation in mouse models and inhibits chronic morphine-induced addiction[1].

[Related Catalog]:

Research Areas >> Neurological Disease

[Target]

PKM2[1]

[References]

[1]. Jin S, et al. Cannabidiol Analogue CIAC001 for the Treatment of Morphine-Induced Addiction by Targeting PKM2. J Med Chem. 2023 Aug 24;66(16):11498-11516.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₂₅N₃O₂

[ Molecular Weight ]:
339.43

Related Compounds

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