TP0597850

Names

[ Name ]:
TP0597850

[Description]:

TP0597850 is a selective inhibitor of MMP2 (IC50=0.22 nM). TP0597850 has a long MMP2 dissociation half-life (t1/2=265 min)[1].

[Related Catalog]:

Research Areas >> Cancer

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Metabolic Enzyme/Protease >> MMP

[Target]

MMP2:0.22 nM (IC50)

MMP-12:250 nM (IC50)

MMP13:240 nM (IC50)

[In Vitro]

TP0597850 (化合物 18) 在广谱 pH 值下表现出极高的化学稳定性[1]。 TP0597850 的抑制常数 Ki 值为 0.034 nM[1]。

[References]

[ Molecular Formula ]:
C₄₁H₅₇N₉O₁₃S

[ Molecular Weight ]:
916.01