JG-23

Names

[ Name ]:
JG-23

Biological Activity

[Description]:

JG-23 is a 4-chloro modified analog with ability to promote t-tau degradation. JG-23 exhibits good metabolic stability with a long T1/2 value (36 min) in mouse liver microsome assays[1].

[Related Catalog]:

Research Areas >> Neurological Disease

[References]

[1]. Shao H, et al. Inhibitors of heat shock protein 70 (Hsp70) with enhanced metabolic stability reduce tau levels. Bioorg Med Chem Lett. 2021 Jun 1;41:128025.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₁₆ClN₃OS₂

[ Molecular Weight ]:
401.93

Related Compounds

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