IACS-52825

Names

[ Name ]:
IACS-52825

Biological Activity

[Description]:

IACS-52825 is a potent and selective DLK inhibitor with Kd of 1.3 nM, useful for the study of chemotherapy-induced peripheral neuropathy[1].

[Related Catalog]:

Research Areas >> Neurological Disease

Signaling Pathways >> MAPK/ERK Pathway >> MAP3K

[References]

[1]. Kang Le, et al. Discovery of IACS-52825, a Potent and Selective DLK Inhibitor for Treatment of Chemotherapy-Induced Peripheral Neuropathy. J Med Chem. 2023 Jul 27;66(14):9954-9971.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₁₃F₇N₄O₂

[ Molecular Weight ]:
426.29

Related Compounds

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