2,4-Dihydroxy-5,6-dimethylpyrimidine
Names
[ CAS No. ]:
26305-13-5
[ Name ]:
2,4-Dihydroxy-5,6-dimethylpyrimidine
[Synonym ]:
5,6-dimethylpyrimidine-2,4-dione
2,4-Dihydroxy-5,6-dimethylpyrimidine
5,6-Dimethyl-2,4(1H,3H)-pyrimidinedione
5,6-dimethylpyrimidine-2,4-diol
5,6-DIMETHYLURACIL
5,6-Dimethylpyrimidine-2,4(1H,3H)-dione
2,4(1H,3H)-Pyrimidinedione, 5,6-dimethyl-
EINECS 247-601-6
Uracil,5,6-dimethyl
5,6-dimethyl-2,4-(1H,3H)-pyrimidinedione
MFCD00010708
6-Methylthymine
5,6-Dimethyl-2,4-pyrimidinediol
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
408.8ºC at 760mmHg
[ Melting Point ]:
297-300 °C (dec.)(lit.)
[ Molecular Formula ]:
C6H8N2O2
[ Molecular Weight ]:
140.140
[ Flash Point ]:
201ºC
[ Exact Mass ]:
140.058578
[ PSA ]:
65.72000
[ LogP ]:
0.47
[ Vapour Pressure ]:
2.88E-07mmHg at 25°C
[ Index of Refraction ]:
1.482
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YQ9750000
- CHEMICAL NAME :
- Uracil, 5,6-dimethyl-
- CAS REGISTRY NUMBER :
- 26305-13-5
- LAST UPDATED :
- 199206
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C6-H8-N2-O2
- MOLECULAR WEIGHT :
- 140.16
- WISWESSER LINE NOTATION :
- T6MVMVJ E1 F1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 140 mg/kg
- TOXIC EFFECTS :
- Behavioral - antipsychotic
- REFERENCE :
- CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 6,490,1958
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Safety Phrases ]:
S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
YQ9750000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Bioorg. Med. Chem. Lett. 20(19) , 5735-8, (2010)
A series of pyrimidine derivatives as acid pump antagonists (APAs) was synthesized and the inhibitory activities against H(+)/K(+) ATPase isolated from hog gastric mucosa were determined. After elabor...
A family of titanium (IV) alkoxo complexes with N, O and O, O chelating ligands. Crystal structure of [Ti (O-i-Pr)2{2-(-)-menthoxo-pyridine}2]. Pérez Y, et al.Inorganica Chim. Acta 360(2) , 607-618, (2007)