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αvβ5 integrin-IN-1

Names

[ CAS No. ]:
2615912-33-7

[ Name ]:
αvβ5 integrin-IN-1

Biological Activity

[Description]:

αvβ5 integrin-IN-1 is a first potent and selective αvβ5 integrin inhibitor (pIC50 = 8.2) .

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cytoskeleton >> Integrin

[References]

[1]. Lippa RA, et al. Discovery of the first potent and selective αvβ5 integrin inhibitor based on an amide-containing core. Eur J Med Chem. 2020 Dec 15;208:112719.

Chemical & Physical Properties

[ Molecular Formula ]:
C25H28F3N3O3

[ Molecular Weight ]:
475.50

Related Compounds