Tenofovir-C3-O-C15-CF3 ammonium

Names

[ Name ]:
Tenofovir-C3-O-C15-CF3 ammonium

Biological Activity

[Description]:

Tenofovir-C3-O-C15-CF3 (ammonium) exhibits substantially longer t1/2 values than tenofovir in human liver microsomes, potent anti-HIV activity in vitro, and enhances pharmacokinetic properties in vivo.

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HIV

Research Areas >> Infection

[References]

[1]. Pribut N, et al. ω-Functionalized Lipid Prodrugs of HIV NtRTI Tenofovir with Enhanced Pharmacokinetic Properties. J Med Chem. 2021 Sep 9;64(17):12917-12937.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₈H₅₂F₃N₆O₅P

[ Molecular Weight ]:
640.72

Tenofovir-C3-O-C15-CF3 ammonium

Names

Biological Activity

Chemical & Physical Properties

Related Compounds