Tazemetostat de(methylene morpholine)-O-C3-O-C-COOH

Names

[ CAS No. ]:
2750350-39-9

[ Name ]:
Tazemetostat de(methylene morpholine)-O-C3-O-C-COOH

Biological Activity

[Description]:

Tazemetostat de(methylene morpholine)-O-C3-O-C-COOH (Compound 21b) is an EZH2 degrader and can be used for the research of lymphoma[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Epigenetics >> Histone Methyltransferase

[Target]

EZH2


[References]

[1]. Tu Y, et al. Design, Synthesis, and Evaluation of VHL-Based EZH2 Degraders to Enhance Therapeutic Activity against Lymphoma. J Med Chem. 2021 Jul 22;64(14):10167-10184.  

Chemical & Physical Properties

[ Molecular Formula ]:
C34H43N3O7

[ Molecular Weight ]:
605.72